Protocol · PT · OT · RT

ABCDEF ICU Bundle

PTOTRT39 citations · 4 lenses

68% mortality reduction when fully implemented. Reduced ICU-acquired weakness, delirium, and ventilator days. SCCM-endorsed. Strong implementation science base.

Score anatomy · every lens
Faculty recognition ×25
55/100

Strong for acute care/CCS-aligned faculty; less weight outside acute tracks.

Scholarship signal ×20
80/100

SCCM-backed with robust ICU liberation literature.

Teaching value ×15
75/100

Core content for acute care and cardiopulmonary curricula.

Evidence depth ×20
85/100

Strong RCT and implementation-science evidence base.

Faculty demand ×10
45/100

Preferred for acute-care faculty lines; niche otherwise.

Credential investment ×10
85/100

Cheap and fast to acquire.

Sources · 39 on file
34 other4 peer-reviewed1 government
  1. 01
    From Strict Bedrest to Early Mobilization: A History of Physiotherapy in the Intensive Care Unit
    M. E. Kho; B. Connolly · Crit Care Clin · 2023
    Otherdoi:10.1016/j.ccc.2023.01.003
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  2. 02
    Caring for Critically Ill Children With the ICU Liberation Bundle (ABCDEF): Results of the Pediatric Collaborative
    J. C. Lin; A. Srivastava; S. Malone; S. Jennison; M. Simino; C. Traube; K. LaRose; Y. Kawai; L. Neu; S. Kudchadkar; B. Wieczorek; K. Hajnik; C. M. Kordik; V. K. Kumar; S. Aghamohammadi; G. M. Arteaga; H. A. B. Smith; T. Spentzas; A. Orman; B. M. Landman; H. Valdivia; H. Browne; T. Fang; J. J. Zimmerman · Pediatr Crit Care Med · 2023
    Otherdoi:10.1097/pcc.0000000000003262
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  3. 03
    An Exploration of Critical Care Professionals' Strategies to Enhance Daily Implementation of the Assess, Prevent, and Manage Pain; Both Spontaneous Awakening and Breathing Trials; Choice of Analgesia and Sedation; Delirium Assess, Prevent, and Manage; Early Mobility and Exercise; and Family Engagement and Empowerment: A Group Concept Mapping Study
    L. C. Mion; A. Tan; A. Brockman; J. A. Tate; E. E. Vasilevskis; B. T. Pun; S. R. Rosas; M. C. Balas · Crit Care Explor · 2023
    Otherdoi:10.1097/cce.0000000000000872
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  4. 04
    Effect of early mobilisation on long-term cognitive impairment in critical illness in the USA: a randomised controlled trial
    B. K. Patel; K. S. Wolfe; S. B. Patel; K. C. Dugan; C. L. Esbrook; A. J. Pawlik; M. Stulberg; C. Kemple; M. Teele; E. Zeleny; D. Hedeker; A. S. Pohlman; V. M. Arora; J. B. Hall; J. P. Kress · Lancet Respir Med · 2023
    RCTdoi:10.1016/s2213-2600(22)00489-1
    DOI ↗
  5. 05
    The Effects of Early Mobilization on Acquired Weakness in Intensive Care Units: A Literature Review
    D. Rosa; A. Negro; I. Marcomini; R. Pendoni; B. Albabesi; G. Pennino; S. Terzoni; A. Destrebecq; G. Villa · Dimens Crit Care Nurs · 2023
    Narrative reviewdoi:10.1097/dcc.0000000000000575
    DOI ↗
  6. 06
    The effect of the ABCDE/ABCDEF bundle on delirium, functional outcomes, and quality of life in critically ill patients: A systematic review and meta-analysis
    K. Sosnowski; F. Lin; W. Chaboyer; K. Ranse; A. Heffernan; M. Mitchell · International Journal of Nursing Studies · 2023
    Meta-analysisdoi:10.1016/j.ijnurstu.2022.104410
    DOI ↗
  7. 07
    Early Mobilization for Critically Ill Patients
    X. Yang; T. Zhang; L. Cao; L. Ye; W. Song · Respir Care · 2023
    Otherdoi:10.4187/respcare.10481
    DOI ↗
  8. 08
    Effects of a National Quality Improvement Collaborative on ABCDEF Bundle Implementation
    M. C. Balas; A. Tan; B. T. Pun; E. W. Ely; S. S. Carson; L. Mion; M. A. Barnes-Daly; E. E. Vasilevskis · Am J Crit Care · 2022
    Otherdoi:10.4037/ajcc2022768
    DOI ↗
  9. 09
    Improving ABCDEF Bundle Compliance and Clinical Outcomes in the ICU: Randomized Control Trial to Assess the Impact of Performance Measurement, Feedback, and Data Literacy Training
    J. C. Brown; J. A. Querubin; L. Ding; W. J. Mack; K. Chen-Chan; F. Perez; J. Barr; C. J. Peden; J. P. Cobb · Crit Care Explor · 2022
    RCTdoi:10.1097/cce.0000000000000679
    DOI ↗
  10. 10
    Modified ABCDEF-Bundles for Critically Ill Pediatric Patients - What Could They Look Like?
    J. Engel; F. von Borell; I. Baumgartner; M. Kumpf; M. Hofbeck; J. Michel; F. Neunhoeffer · Front Pediatr · 2022
    Otherdoi:10.3389/fped.2022.886334
    DOI ↗
  11. 11
    Early Active Mobilization during Mechanical Ventilation in the ICU
    C. L. Hodgson; M. Bailey; R. Bellomo; K. Brickell; T. Broadley; H. Buhr; B. J. Gabbe; D. W. Gould; M. Harrold; A. M. Higgins; S. Hurford; T. J. Iwashyna; A. Serpa Neto; A. D. Nichol; J. J. Presneill; S. J. Schaller; J. Sivasuthan; C. J. Tipping; S. Webb; P. J. Young · N Engl J Med · 2022
    Otherdoi:10.1056/NEJMoa2209083
    DOI ↗
  12. 12
    ABCDEF Bundle Practices for Critically Ill Children: An International Survey of 161 PICUs in 18 Countries
    E. Ista; J. Redivo; P. Kananur; K. Choong; J. Colleti Jr; D. M. Needham; R. Awojoodu; S. R. Kudchadkar; J. Colleti, Jr.; P.-P. I. International · Critical Care Medicine · 2022
    Cross-sectionaldoi:10.1097/CCM.0000000000005168
    DOI ↗
  13. 13
    Association of Incident Delirium With Short-term Mortality in Adults With Critical Illness Receiving Mechanical Ventilation
    H.-C. Li; T. Y.-C. Yeh; Y.-C. Wei; S.-C. Ku; Y.-J. Xu; C. C.-H. Chen; S. Inouye; L. M. Boehm · JAMA Network Open · 2022
    Otherdoi:10.1001/jamanetworkopen.2022.35339
    DOI ↗
  14. 14
    A Quality Improvement Initiative to Evaluate the Effectiveness of the ABCDEF Bundle on Sepsis Outcomes
    R. A. Loberg; B. A. Smallheer; J. A. Thompson · Critical Care Nursing Quarterly · 2022
    Otherdoi:10.1097/CNQ.0000000000000387
    DOI ↗
  15. 15
    ABCDE and ABCDEF care bundles: A systematic review of the implementation process in intensive care units
    F. D. S. Moraes; L. L. Marengo; M. D. G. Moura; C. C. Bergamaschi; F. de Sá Del Fiol; L. C. Lopes; M. T. Silva; S. Barberato-Filho · Medicine (Baltimore) · 2022
    Systematic reviewdoi:10.1097/md.0000000000029499
    DOI ↗
  16. 16
    Interprofessional Team Collaboration and Work Environment Health in 68 US Intensive Care Units
    B. T. Pun; J. Jun; A. Tan; D. Byrum; L. Mion; E. E. Vasilevskis; E. W. Ely; M. Balas · American Journal of Critical Care · 2022
    Otherdoi:10.4037/ajcc2022546
    DOI ↗
  17. 17
    Variables associated with mobility levels in critically ill patients: A cohort study
    M. Raurell-Torredà; S. Arias-Rivera; J. D. Martí; M. J. Frade-Mera; I. Zaragoza-García; E. Gallart; T. R. Velasco-Sanz; A. San José-Arribas; E. Blazquez-Martínez · Nurs Crit Care · 2022
    Cohort studydoi:10.1111/nicc.12639
    DOI ↗
  18. 18
    Using a real-time ABCDEF compliance tool to understand the role of bundle elements in mortality and delirium
    J. C. Shampo; K. Wenszell; X. Luo-Owen; N. Mukherjee; M. Cochran-Yu; L. Swentek; S. K. Burruss; S. Markovich; D. Turay; I. R. Dorotta; K. Mukherjee · J Trauma Acute Care Surg · 2022
    Otherdoi:10.1097/ta.0000000000003622
    DOI ↗
  19. 19
    2022 Society of Critical Care Medicine Clinical Practice Guidelines on Prevention and Management of Pain, Agitation, Neuromuscular Blockade, and Delirium in Critically Ill Pediatric Patients With Consideration of the ICU Environment and Early Mobility
    H. A. B. Smith; J. B. Besunder; K. A. Betters; P. N. Johnson; V. Srinivasan; A. Stormorken; E. Farrington; B. Golianu; A. J. Godshall; L. Acinelli; C. Almgren; C. H. Bailey; J. M. Boyd; M. J. Cisco; M. Damian; M. L. deAlmeida; J. Fehr; K. E. Fenton; F. Gilliland; M. J. C. Grant; J. Howell; C. A. Ruggles; S. Simone; F. Su; J. E. Sullivan; K. Tegtmeyer; C. Traube; S. Williams; J. W. Berkenbosch · Pediatr Crit Care Med · 2022
    Otherdoi:10.1097/pcc.0000000000002873
    DOI ↗
  20. 20
    Impact of Pain, Agitation, and Delirium Bundle on Delirium and Cognitive Function
    X. P. Wang; D. Lv; Y. F. Chen; N. Chen; X. D. Li; C. F. Xu; Y. Li; L. Tian · J Nurs Res · 2022
    Otherdoi:10.1097/jnr.0000000000000497
    DOI ↗
  21. 21
    Physical Rehabilitation in the ICU: A Systematic Review and Meta-Analysis
    Y. T. Wang; J. K. Lang; K. J. Haines; E. H. Skinner; T. P. Haines · Crit Care Med · 2022
    Meta-analysisdoi:10.1097/ccm.0000000000005285
    DOI ↗
  22. 22
    The Impact of a Multidisciplinary Education Program for Intensive Care Unit Staff Regarding Ventilator Care Bundle on the Frequency of Ventilator-Associated Events
    E. Adiyeke; B. I. Koc; N. Coskun; N. Bakan; E. Sen; A. Turan; H. Ozturk · Dimens Crit Care Nurs · 2021
    Otherdoi:10.1097/dcc.0000000000000484
    DOI ↗
  23. 23
    Assess, Prevent, and Manage Pain; Both Spontaneous Awakening and Breathing Trials; Choice of Analgesia/Sedation; Delirium: Assess, Prevent, and Manage; Early Mobility; Family Engagement and Empowerment Bundle Implementation: Quantifying the Association of Access to Bundle-Enhancing Supplies and Equipment
    A. D. Jeffery; J. A. Werthman; V. Danesh; M. S. Dietrich; L. C. Mion; L. M. Boehm · Crit Care Explor · 2021
    Otherdoi:10.1097/cce.0000000000000525
    DOI ↗
  24. 24
    Implementation of ABCDEF care bundle in intensive care units: A cross-sectional survey
    S. Liang; J. P. C. Chau; S. H. S. Lo; S. Li; M. Gao · Nurs Crit Care · 2021
    Cross-sectionaldoi:10.1111/nicc.12597
    DOI ↗
  25. 25
    Implementation of the ABCDEF Bundle for Critically Ill ICU Patients During the COVID-19 Pandemic: A Multi-National 1-Day Point Prevalence Study
    K. Liu; K. Nakamura; H. Katsukawa; P. Nydahl; E. W. Ely; S. R. Kudchadkar; K. Takahashi; M. Elhadi; M. Gurjar; B. K. Leong; C. R. Chung; J. Balachandran; S. Inoue; A. K. Lefor; O. Nishida · Front Med (Lausanne) · 2021
    Otherdoi:10.3389/fmed.2021.735860
    DOI ↗
  26. 26
    Prevention and Management of Delirium in the Intensive Care Unit
    M. F. Mart; S. Williams Roberson; B. Salas; P. P. Pandharipande; E. W. Ely · Seminars in Respiratory & Critical Care Medicine · 2021
    Otherdoi:10.1055/s-0040-1710572
    DOI ↗
  27. 27
    Systematic early versus late mobilization or standard early mobilization in mechanically ventilated adult ICU patients: systematic review and meta-analysis
    D. Menges; B. Seiler; Y. Tomonaga; M. Schwenkglenks; M. A. Puhan; H. G. Yebyo · Crit Care · 2021
    Meta-analysisdoi:10.1186/s13054-020-03446-9
    DOI ↗
  28. 28
    Early mobilisation algorithm for the critical patient. Expert recommendations
    M. Raurell-Torredà; E. Regaira-Martínez; B. Planas-Pascual; R. Ferrer-Roca; J. D. Martí; E. Blazquez-Martínez; G. Ballesteros-Reviriego; I. Vinuesa-Suárez; G. Zariquiey-Esteva · Enferm Intensiva (Engl Ed) · 2021
    Otherdoi:10.1016/j.enfie.2020.11.001
    DOI ↗
  29. 29
    Algoritmo de movilización temprana para el paciente crítico. Recomendaciones de expertos
    M. Raurell-Torredà; E. Regaira-Martínez; B. Planas-Pascual; R. Ferrer-Roca; J. D. Martí; E. Blazquez-Martínez; G. Ballesteros-Reviriego; I. Vinuesa-Suárez; G. Zariquiey-Esteva · Enfermería Intensiva · 2021
    Otherdoi:10.1016/j.enfi.2020.11.001
    DOI ↗
  30. 30
    Evaluating the Cost-Effectiveness of the ABCDE Bundle: Impact of Bundle Adherence on Inpatient and 1-Year Mortality and Costs of Care
    A. W. Collinsworth; E. L. Priest; A. L. Masica · Crit Care Med · 2020
    Otherdoi:10.1097/ccm.0000000000004609
    DOI ↗
  31. 31
    Clinical Practice Guidelines for Early Mobilization in the ICU: A Systematic Review
    J. K. Lang; M. S. Paykel; K. J. Haines; C. L. Hodgson · Crit Care Med · 2020
    Systematic reviewdoi:10.1097/ccm.0000000000004574
    DOI ↗
  32. 32
    Physical Therapy and Rehabilitation in Chronic Obstructive Pulmonary Disease Patients Admitted to the Intensive Care Unit
    J. D. Martí; D. McWilliams; E. Gimeno-Santos · Semin Respir Crit Care Med · 2020
    Otherdoi:10.1055/s-0040-1709139
    DOI ↗
  33. 33
    Effects of Inspiratory Muscle Training and Early Mobilization on Weaning of Mechanical Ventilation: A Systematic Review and Network Meta-analysis
    S. Worraphan; A. Thammata; K. Chittawatanarat; S. Saokaew; K. Kengkla; M. Prasannarong · Arch Phys Med Rehabil · 2020
    Meta-analysisdoi:10.1016/j.apmr.2020.07.004
    DOI ↗
  34. 34
    The effect of early mobilization in critically ill patients: A meta-analysis
    K. Zang; B. Chen; M. Wang; D. Chen; L. Hui; S. Guo; T. Ji; F. Shang · Nurs Crit Care · 2020
    Meta-analysisdoi:10.1111/nicc.12455
    DOI ↗
  35. 35
    The ABCDEF Bundle: Science and Philosophy of How ICU Liberation Serves Patients and Families
    Ely EW · Critical Care Medicine · 2017
    Establishes the ABCDEF bundle as a programmatic research framework with a defined investigator pipeline (SCCM ICU Liberation Collaborative), which is the entry point junior researchers use to build a PI-track portfolio in implementation science.
    Otherdoi:10.1097/CCM.0000000000002175
    DOI ↗
  36. 36
    Caring for Critically Ill Patients with the ABCDEF Bundle: Results of the ICU Liberation Collaborative in Over 15,000 Adults
    Pun BT, Balas MC, Barnes-Daly MA, et al. · Critical Care Medicine · 2019
    Demonstrates that the ICU Liberation Collaborative functions as a large multi-site research network producing co-authorship and dataset access opportunities, a key K-to-R transition asset for trainees pursuing independent PI careers in critical care.
    Otherdoi:10.1097/CCM.0000000000003482
    DOI ↗
  37. 37
    PAR-22-181: Mentored Patient-Oriented Research Career Development Award (K23)
    National Institutes of Health, NHLBI · NIH Guide for Grants and Contracts · 2022
    NHLBI explicitly funds K23 awards in critical care delirium, sedation, and post-ICU outcomes research; domains directly aligned with ABCDEF bundle elements; making bundle expertise a fundable K-award niche for clinician-scientists.
    Othergovernment
    DOI ↗
  38. 38
    Interprofessional collaboration to improve professional practice and healthcare outcomes
    Reeves S, Pelone F, Harrison R, Goldman J, Zwarenstein M · Cochrane Database of Systematic Reviews · 2017
    Validates interprofessional implementation bundles (the ABCDEF model) as a recognized methodological domain in dissemination and implementation science, the field NIH Office of Behavioral and Social Sciences funds for independent investigator development.
    Otherdoi:10.1002/14651858.CD000072.pub3
    DOI ↗
  39. 39
    Implementation research in mental health services: an emerging science with conceptual, methodological, and training challenges
    Proctor EK, Landsverk J, Aarons G, Chambers D, Glisson C, Mittman B · Administration and Policy in Mental Health and Mental Health Services Research · 2009
    Defines implementation-science training competencies (the framework under which ABCDEF bundle research is funded by NIH PAR-19-274 implementation-science mechanisms), establishing the credential's relevance to a PI career trajectory in D&I science.
    Otherdoi:10.1007/s10488-008-0197-4
    DOI ↗
All credentials Methodology
Open in the field